David FOLIO’s research activities regularly lead him to collaborate in various scientific projects that is listed here.
Scientific projects aim to obtain funding for recruiting students, designing or improving experimental testbeds, and promoting scientific collaborations. Below is a list of the projects I have been involved in, including my role and the funding obtained. It is important to note that all of these projects have undergone a rigorous scientific review process.
Current Projets
BUBBLEBOT: Magnetic microbubbles for the targeted delivery of therapeutic agent in the brain
- Date
-
10/2020 – 10/2023
- Funding
-
210k€, supported by Région Centre Val de Loire (APR-IR)
- Summary
-
The aim is to combine the progress made in microrobotics with those linked to the original microbubbles developed in order to improve the therapeutic targeting of glioblastoma.
- Role
-
Principal Investigator (PI), and co-supervision of the PhD thesis of Karim Botros.
Old projects
European Union (EU) and National Funding (ANR) Projects
MTG: Microrobots Targeting Glioblastoma
- Date
-
03/2019 – 03/2022
- Funding
-
511.4k€, supported by French National Institute of Health and Medical Research1 (Inserm)
- Summary
-
The MTG project is an Inserm, “plan cancer” project. The objective is to functionalize magnetic microrobot with NFL peptide2 to target glioblastoma (GBM).
- Role
-
Co-responsible of the workpackage WP3: “in vitro and in vivo distribution and tracking studies using IVIS imaging system to test the capacity of MTG to target glioblastoma cells versus healthy cells of the nervous system”.
PIANHO: Innovative Haptic Instrumental platform for 3D Nano-manipulation
- Date
-
03/2010 – 03/2014
- Funding
-
761k€, supported by French national funding (ANR)
- Summary
-
The PIANHO project is an ANR3 P3N (2009) project.
The motivation of this project is to create a nanomanipulation platform capable of pick, hold and place nano-objects in the synchrotron radiation beam of the ESRF (Grenoble, France) via customizable tool-object interaction. - Role
-
Co-responsible of the workpackage: “Control of a Two-Fingered AFM-based Nano-manipulation System”, and co-supervision of the PhD thesis of Nabil Amari.
PROTEUS: Robotic Platform to facilitate transfer between industries
- Date
-
12/2009 – 12/2013
- Funding
-
2.1M€, supported by French national funding (ANR)
- Summary
-
The PROTEUS project is an ANR ARPEGE program (2009) project.
This project motivation was to help organizing interactions between academic and industrial partners of the french robotic community by providing suitable tools and models. Especially, one goal is to create a portal for the French robotic community as embodied by the GDR Robotique and its affiliated industrial partners, in order to facilitate transfer of knowledge and problems among this community. To achieve the PROTEUS project 12 partners have been involved. - Role
-
Co-responsible of the workpackage: “Young Challenge”.
PROSIT : Robotic Platform for an Interactive Tele-echographic Systems
- Date
-
01/2009 – 09/2012
- Funding
-
230k€, supported by French national funding (ANR)
- Summary
-
The PROSIT project is an ANR Contint program (2008) project, coordinated by Professor Pierre Vieyres, University of Orléans, PRISME Laboratory.
The goal is to develop an interactive and complex master-slave robotic platform for a medical diagnosis application (i.e., tele-echography) based on a well-defined modular control architecture. - Role
-
Co-responsible of the workpackage WP5: “Visual Servoing”.
NANOMA : Nano-Actuators and Nano-Sensors for Medical Applications
- Date
-
06/2008 – 10/2011
- Funding
-
3.3M€, supported by the European Commission
- Summary
-
The NANOMA project is an European project funded under FP7 ICT 2007.3.6, Micro/nanosystems, coordinated by Professor Antoine Ferreira, University of Orléans, PRISME Laboratory. The NANOMA project aims at proposing novel controlled nanorobotic delivery systems which will be designed to improve the administration of drugs in the treatment and diagnosis of breast cancer.
- Role
-
Co-responsible of the workpackage WP4: “Object Tracking, Planning and Control in MRI”.
Partnership
PHC4 cooperation program PROCORE between France and Hong-Kong
- Date
-
2014 – 2015
- Summary
-
Supervision and control of an improved platform for targeted administration of therapeutic Nanorobots.
- Partnership
-
Cooperative research work with Prof. Li Zhang of the Department of Mechanical and Automation Engineering (MAE) du Chinese University of Hong Kong (CUHK), Hong-Kong
PHC cooperation program PROCOPE between France and Germany
- Date
-
2010 – 2011
- Summary
-
Design, fabrication and characterization of the swim of enhanced helical microrobots.
- Partnership
-
Cooperative research work with Prof. Dr.-Ing. Sergej Fatikov of the Division Microrobotics and Control Engineering (AMiR5) of the University of Oldenburg, Germany
Local Project
US-Probe: High Definition Echograph
- Date
-
03/2017 – 03/2018
- Funding
-
50k€, supported by Région Centre Val de Loire
- Summary
-
Design of novel microrobotic platform with ultrasound probe vision.
- Role
-
Principal Investigator (PI).
MicroRob:
- Date
-
10/2013 – 09/2016
- Funding
-
110k€, supported by Région Centre-Val de Loire and the agglomeration comity of Bourges.
- Summary
-
Modeling and control of magnetic microcarrier for targeted cancer therapy.
- Role
-
Co-supervision of the PhD thesis of Lyes Mellal.
Nano-IRM:
- Date
-
09/2009 – 08/2012
- Funding
-
110k€, supported by Région Centre-Val de Loire, the Cher (18) departmental councils and the agglomeration comity of Bourges.
- Summary
-
Supervision and Control of an Improved Platform for Targeted Administration of Therapeutic Nanorobots. This project supports the above project NANOMA, by providing the funding for the PhD thesis of Karim Belharet.
- Role
-
Co-supervision of the PhD thesis of Karim Belharet.
Footnotes
From French: Institut national de la santé et de la recherche médicale (INSERM), https://www.inserm.fr↩︎
NeuroFilament Light subunit that is binding Tubulin (NFL peptide) is capable to penetrate in GBM, block and inhibit cell division.↩︎
From French “Agence Nationale de la Recherche” (ANR), which is the French National Agency for Research. http://www.agence-nationale-recherche.fr↩︎
PHC, from French “Partenariats Hubert Curien”, provides support for international scientific and technological exchange of the Ministry of Foreign Affairs. https://www.campusfrance.org↩︎
AMiR, that is from German “Abteilung für Mikrorobotik und Regelungstechnik”, is a department of the University of Oldenburg, Germany, headed by Prof. Dr.-Ing. Sergej Fatikov. http://www.amir.uni-oldenburg.de↩︎